Researchers grow up human liver in lab

Researchers grow up human liver in lab

Researcher at The Institute for Regenerative Medicine at Wake Forest University Baptist Medical Center have successfully managed to produces artificial human liver, about an inch in diameter and weighing in at 0.2 ounces. Its smaller in size than the human actually have in their body, but we hope its just beginning of development.

To engineer the organs, the scientists took animal livers and treated them with a mild detergent to remove all cells in a process called decellularization. This left only the collagen "skeleton" or support structure which allowed the scientists to replace the original cells with two types of human cells: immature liver cells known as progenitors, and endothelial cells that line blood vessels.
Because the network of vessels remains intact after the decellularization process the researchers were able to introduce the cells into the liver skeleton through a large vessel that feeds a system of smaller vessels in the liver. The liver was then placed in a bioreactor, special equipment that provides a constant flow of nutrients and oxygen throughout the organ.



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